Understanding immune cell roles in pancreatic cancer
Core C: CODEX Core
This study is looking at how certain immune cells affect the growth and spread of pancreatic cancer, using advanced techniques to see how these cells behave in tumors over time and with treatments, which could help improve future cancer therapies for patients.
Quick facts
| Grant type | P01 program project |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Stanford University NIH-funded |
| Lab location | 1 site (Stanford, United States) |
| Project ID | NIH-10927316 on NIH RePORTER |
What this research studies
This research investigates how specific immune cell types contribute to the initiation, development, and spread of pancreatic ductal adenocarcinoma (PDAC) in both mouse models and humans. By utilizing a novel technique called CO-Detection by indEXing (CODEX), the study aims to analyze the frequency, spatial relationships, and activation states of these cells within tumors over time and in response to therapies. Patients may benefit from insights gained about the immune system's role in cancer progression and treatment responses, which could lead to improved therapeutic strategies.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals diagnosed with pancreatic ductal adenocarcinoma who are undergoing treatment or are in the early stages of the disease.
Not a fit: Patients with other types of cancer or those who do not have pancreatic cancer may not receive direct benefits from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective treatments for pancreatic cancer by enhancing our understanding of immune cell interactions within tumors.
How similar studies have performed: Previous research using similar immune profiling techniques has shown promise in understanding cancer biology and improving treatment outcomes.
Where this research is happening
Stanford, United States
- Stanford University — Stanford, United States (Active)
Researchers
- Principal investigator: Kim, Seung K — Stanford University
- Study coordinator: Kim, Seung K
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.