Understanding immune cell interactions and their role in lymphocyte-related diseases
BLRD Research Career Scientist Award Application
This study is looking at how certain proteins help immune cells work better to fight cancers like B cell lymphoma and multiple myeloma, especially in veterans, with the hope of finding better treatments for those affected.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Iowa City VA Medical Center NIH-funded |
| Lab location | 1 site (Iowa City, United States) |
| Project ID | NIH-10948090 on NIH RePORTER |
What this research studies
This research focuses on the molecular mechanisms that regulate immune cell functions, particularly B and T lymphocytes, and how these cells contribute to cancers like B cell lymphoma and multiple myeloma. The project aims to uncover the role of specific proteins, such as TRAF3, in preventing these cancers, which are prevalent among veterans. By collaborating with physician-scientists, the research seeks to translate basic science findings into clinical applications, potentially leading to improved treatment strategies for affected patients. The ultimate goal is to enhance the selection of optimal treatments for veterans suffering from these conditions.
Who could benefit from this research
Good fit: Ideal candidates for this research include veterans diagnosed with B cell lymphoma or multiple myeloma.
Not a fit: Patients with lymphocyte-related diseases who are not veterans may not receive direct benefits from this research.
Why it matters
Potential benefit: If successful, this research could lead to better prevention and treatment options for lymphocyte-related cancers, particularly in the veteran population.
How similar studies have performed: Previous research has shown promise in understanding immune cell interactions and their implications in cancer, suggesting that this approach could yield significant insights.
Where this research is happening
Iowa City, United States
- Iowa City VA Medical Center — Iowa City, United States (Active)
Researchers
- Principal investigator: Bishop, Gail a. — Iowa City VA Medical Center
- Study coordinator: Bishop, Gail a.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.