Understanding immature tumor cells in pediatric rhabdomyosarcoma
The Role of Immature Tumor Subpopulations In Pediatric Rhabdomyosarcoma
['FUNDING_R01'] · ST. JUDE CHILDREN'S RESEARCH HOSPITAL · NIH-11031369
This study is looking at how certain early-stage cells in rhabdomyosarcoma, a cancer that mainly affects kids, behave during treatment to help understand why some children might have their cancer come back, with the hope of creating better, personalized treatments for them.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | ST. JUDE CHILDREN'S RESEARCH HOSPITAL (nih funded) |
| Locations | 1 site (MEMPHIS, UNITED STATES) |
| Trial ID | NIH-11031369 on ClinicalTrials.gov |
What this research studies
This research investigates the role of immature tumor subpopulations in rhabdomyosarcoma, a type of cancer that primarily affects children. The team will analyze tumor samples using advanced computational methods to identify different cell types within the tumors and their genetic characteristics. By studying how these immature cells behave during and after treatment, the researchers aim to uncover why some patients experience cancer recurrence. This knowledge could lead to the development of more effective therapies tailored to individual patient needs.
Who could benefit from this research
Good fit: Ideal candidates for this research are children diagnosed with rhabdomyosarcoma, particularly those who have undergone treatment and are at risk of recurrence.
Not a fit: Patients with other types of cancer or those who are not diagnosed with rhabdomyosarcoma may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved treatment strategies that reduce the risk of cancer recurrence in pediatric patients with rhabdomyosarcoma.
How similar studies have performed: Other research has shown promise in understanding tumor heterogeneity and its implications for treatment, suggesting that this approach could yield valuable insights.
Where this research is happening
MEMPHIS, UNITED STATES
- ST. JUDE CHILDREN'S RESEARCH HOSPITAL — MEMPHIS, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: CHEN, XIANG — ST. JUDE CHILDREN'S RESEARCH HOSPITAL
- Study coordinator: CHEN, XIANG
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: anti-cancer research