Understanding IAP's Role in Placenta Development
The role of the endogenous retroviral family, IAP, in placentation.
['FUNDING_R01'] · STANFORD UNIVERSITY · NIH-11127657
This research explores how a specific family of genetic elements, called IAP, helps the placenta grow and function during pregnancy.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | STANFORD UNIVERSITY (nih funded) |
| Locations | 1 site (STANFORD, UNITED STATES) |
| Trial ID | NIH-11127657 on ClinicalTrials.gov |
What this research studies
Our bodies contain ancient genetic material from viruses, called endogenous retroviruses (ERVs), which play many important roles, including helping cells communicate. This project focuses on a particular ERV family, IAP, and its function at the maternal-fetal interface, which is where the mother and baby connect through the placenta. We aim to understand how IAP contributes to healthy placenta development, both inside cells and by sending messages between cells. By studying these processes, we hope to uncover new insights into how pregnancies progress.
Who could benefit from this research
Good fit: This foundational research is not directly recruiting patients but aims to benefit future pregnant individuals by improving knowledge of placental health.
Not a fit: Patients not experiencing pregnancy-related conditions or those seeking immediate treatment may not directly benefit from this basic science research.
Why it matters
Potential benefit: If successful, this work could lead to a deeper understanding of healthy placenta development, potentially informing future strategies to prevent pregnancy complications.
How similar studies have performed: Prior research has shown that similar viral-like particles are present in placentas across many species, including humans, supporting the importance of this area of study.
Where this research is happening
STANFORD, UNITED STATES
- STANFORD UNIVERSITY — STANFORD, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: BAKER, JULIE C — STANFORD UNIVERSITY
- Study coordinator: BAKER, JULIE C
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.