Understanding human genetic differences through evolution
The impact of natural selection and population structure on human genomic variation
This project helps us understand how our genes change over time and how different human groups came to have their unique genetic makeups.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California at Davis NIH-funded |
| Lab location | 1 site (Davis, United States) |
| Project ID | NIH-11090891 on NIH RePORTER |
What this research studies
This project uses vast amounts of genetic data, including ancient DNA, to explore how natural selection and population movements have influenced human genetic variation. Researchers are developing new statistical tools to analyze these complex datasets, looking at how genes change over different time periods and how populations have spread. They also aim to improve how we interpret genetic findings from large-scale studies by considering family histories. This work helps us better understand the genetic roots of human traits and diseases.
Who could benefit from this research
Good fit: This foundational genetic research does not directly involve patient participation, but its insights could eventually benefit anyone interested in their genetic heritage or those with conditions influenced by genetic factors.
Not a fit: Patients seeking immediate clinical interventions or direct treatment options would not find direct benefit from this basic science project.
Why it matters
Potential benefit: If successful, this work could lead to a deeper understanding of human genetic diversity, which might improve how we predict disease risk and develop personalized treatments in the future.
How similar studies have performed: This project builds upon existing knowledge in population genetics and statistics, developing novel tools to analyze new and extensive genomic datasets.
Where this research is happening
Davis, United States
- University of California at Davis — Davis, United States (Active)
Researchers
- Principal investigator: Coop, Graham — University of California at Davis
- Study coordinator: Coop, Graham
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.