Understanding how Zika virus affects brain development in infants
Early neural predictors and neuropathogenesis of sensorimotor neurodevelopmental deficits in macaque infants exposed to Zika virus in utero
This study is looking at how being exposed to the Zika virus before birth might affect babies' brain development, using monkeys to help understand what changes happen in the brain and how we can spot any potential challenges early on, so we can better support those children later in life.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Wisconsin-Madison NIH-funded |
| Lab location | 1 site (Madison, United States) |
| Project ID | NIH-10839988 on NIH RePORTER |
What this research studies
This research investigates the impact of prenatal exposure to the Zika virus on the brain development of infants, using rhesus macaques as a model. The study aims to identify early signs of neurodevelopmental deficits and the underlying brain changes that occur due to Zika exposure. By conducting controlled assessments and advanced imaging techniques, researchers hope to predict which infants may face developmental challenges later in life. This knowledge could lead to targeted interventions to support affected children.
Who could benefit from this research
Good fit: Ideal candidates for this research are infants who were exposed to the Zika virus in utero.
Not a fit: Patients who were not exposed to the Zika virus during pregnancy are unlikely to benefit from this research.
Why it matters
Potential benefit: If successful, this research could help identify infants at risk for developmental delays due to Zika virus exposure, allowing for early intervention and support.
How similar studies have performed: Previous research has shown promising results in understanding the effects of viral infections on neurodevelopment, suggesting that this approach could yield valuable insights.
Where this research is happening
Madison, United States
- University of Wisconsin-Madison — Madison, United States (Active)
Researchers
- Principal investigator: Mohr, Emma L — University of Wisconsin-Madison
- Study coordinator: Mohr, Emma L
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.