Understanding how zebrafish regenerate their fins
Molecular and Genetic Analysis of Fin Regeneration in Zebrafish
['FUNDING_OTHER'] · UNIVERSITY OF WISCONSIN-MADISON · NIH-10877059
This study is looking at how zebrafish can regrow their fins, focusing on the special nerve cells that help with this healing process, to find out which genes are important for regeneration and how it works, which could help us understand healing better.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF WISCONSIN-MADISON (nih funded) |
| Locations | 1 site (MADISON, UNITED STATES) |
| Trial ID | NIH-10877059 on ClinicalTrials.gov |
What this research studies
This research investigates the molecular and genetic mechanisms behind fin regeneration in zebrafish, a model organism known for its remarkable regenerative abilities. By focusing on the role of specific neuronal subtypes and their influence on tissue regeneration, the study aims to identify key genes involved in this process. Researchers will utilize advanced genetic screening techniques to uncover mutations that affect regeneration, particularly those related to ion channels. This work could provide insights into the fundamental biology of regeneration and its evolutionary aspects.
Who could benefit from this research
Good fit: Ideal candidates for participation or benefit from this research would include individuals with conditions that impair tissue regeneration or healing.
Not a fit: Patients with conditions unrelated to tissue regeneration or those not experiencing healing impairments may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to breakthroughs in regenerative medicine, potentially improving healing processes in humans.
How similar studies have performed: Other research has shown success in using zebrafish as a model for studying regeneration, indicating that this approach is promising and has potential for significant findings.
Where this research is happening
MADISON, UNITED STATES
- UNIVERSITY OF WISCONSIN-MADISON — MADISON, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: KANG, JUNSU — UNIVERSITY OF WISCONSIN-MADISON
- Study coordinator: KANG, JUNSU
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.