Understanding how zebrafish fins grow and regenerate
Illuminating the mechanisms that generate pattern and shape during growth and regeneration of the zebrafish fin
This study looks at how zebrafish fins know where they are in the body so they can grow and heal properly, which could help us understand and improve treatments for people with limb issues.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Boston College NIH-funded |
| Lab location | 1 site (Chestnut Hill, United States) |
| Project ID | NIH-10906193 on NIH RePORTER |
What this research studies
This research investigates how zebrafish fins interpret their biological location to grow and regenerate correctly. By studying the mechanisms that guide the size, pattern, and shape of these fins, researchers aim to uncover the processes that lead to limb malformations and improve regenerative therapies. The study utilizes zebrafish as a model organism due to their remarkable ability to regenerate fins after amputation, providing insights into cellular behavior and positional identity during growth.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with congenital limb disorders or those interested in regenerative therapies.
Not a fit: Patients with non-congenital limb issues or those not seeking regenerative treatments may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to advancements in preventing and treating congenital limb disorders and improving regenerative medicine.
How similar studies have performed: Other research has shown success in using zebrafish models to understand growth and regeneration, making this approach both relevant and promising.
Where this research is happening
Chestnut Hill, United States
- Boston College — Chestnut Hill, United States (Active)
Researchers
- Principal investigator: Mcmenamin, Sarah Kelly — Boston College
- Study coordinator: Mcmenamin, Sarah Kelly
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.