Understanding how ZCWPW1 affects egg quality and fertility.
Official title: Dissecting the role of ZCWPW1 in oocyte quality, fertility and ovarian physiology.
Funded at University of Michigan at Ann Arbor · NIH-10994740 · Data updated 2026-11-12
This study is looking at how a protein called ZCWPW1 affects egg development and fertility in women, which could help us understand fertility issues better and lead to new treatments.
Quick facts
| Grant type | Fellowship grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Michigan at Ann Arbor NIH-funded |
| Lab location | 1 site (Ann Arbor, United States) |
| Project start | September 1, 2024 |
| Project end | August 31, 2027 |
| Funding year | 2024 |
| Award (this year) | $42,545 |
| NIH project number | 1F31HD113285-01A1 |
| Project ID | NIH-10994740 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are women experiencing fertility challenges or those interested in understanding the biological factors affecting egg quality.
✕Less likely to help
Patients who are not female or those who do not have concerns related to fertility may not benefit from this research.
What this research studies
This research investigates the role of a protein called ZCWPW1 in the development of eggs and overall fertility in females. By studying how ZCWPW1 influences the pairing of chromosomes during the cell division process known as meiosis, the researchers aim to uncover its impact on egg quality and ovarian health. The study will involve examining the effects of ZCWPW1 on the survival and elimination of eggs, which could provide insights into fertility issues. Patients may benefit from this research through improved understanding of fertility challenges and potential new treatments.
Why it matters
Potential benefit: If successful, this research could lead to better strategies for addressing fertility issues in women.
How similar studies have gone: Previous research has shown promising results in understanding the genetic factors influencing fertility, making this approach both relevant and potentially impactful.
Where this research is happening
-
University of Michigan at Ann Arbor
Ann Arbor, United States Active
Researchers
- Principal investigator: Bazzano, Dominic — University of Michigan at Ann Arbor
- Study coordinator: Bazzano, Dominic
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.