Understanding how young brains recover from strokes better than adult brains
Official title: Mechanisms of Juvenile Neurogenesis and Post-Stroke Recovery: Determining the Role of Age-Associated Neuroimmune Interactions
Funded at Louisiana State Univ Hsc Shreveport · NIH-11058464 · Data updated 2026-11-12
This study is looking at why young people’s brains bounce back better from strokes than adults, hoping to find ways to help everyone recover better after a stroke.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Louisiana State Univ Hsc Shreveport NIH-funded |
| Lab location | 1 site (Shreveport, United States) |
| Project start | April 15, 2023 |
| Project end | March 31, 2028 |
| Funding year | 2025 |
| Award (this year) | $328,500 |
| NIH project number | 5R01NS131484-03 |
| Project ID | NIH-11058464 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for participation or benefit from this research include children and adolescents who have experienced a stroke, as well as adults seeking improved recovery strategies.
✕Less likely to help
Patients who have not suffered a stroke or those with chronic neurological conditions unrelated to stroke may not benefit from this research.
What this research studies
This research investigates how the brains of young individuals recover from strokes more effectively than those of adults. By studying juvenile models of stroke, the researchers aim to uncover the cellular mechanisms that promote neurogenesis, or the growth of new neurons, in younger brains. The study focuses on the role of immune responses during the acute phase of stroke and how these responses differ between juveniles and adults. The ultimate goal is to identify new treatment targets that could enhance recovery for stroke patients of all ages.
Why it matters
Potential benefit: If successful, this research could lead to new therapies that improve recovery outcomes for stroke patients, particularly by leveraging the unique regenerative capabilities of younger brains.
How similar studies have gone: Previous research has shown that younger brains exhibit greater plasticity and recovery potential after injury, suggesting that this approach could yield significant insights and advancements.
Where this research is happening
-
Louisiana State Univ Hsc Shreveport
Shreveport, United States Active
Researchers
- Principal investigator: Rodgers, Krista — Louisiana State Univ Hsc Shreveport
- Study coordinator: Rodgers, Krista
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.