NIH-funded research R37 grant

Understanding how young adults use nicotine and cannabis together

Official title: Predictors and Consequences of Nicotine and Cannabis Vaping Co-use in Young Adults: A Longitudinal and EMA Analysis

Funded at Rand Corporation · NIH-11057727 · Data updated 2026-11-12

This study is looking at how young adults who use both nicotine and cannabis through vaping are affected by it in their daily lives, aiming to understand how these substances work together and impact their health and happiness.

Quick facts

Grant typeR37 grant
Study typeNIH-funded research
Funding institutionRand Corporation
NIH-funded
Lab location1 site (Santa Monica, United States)
Project startApril 1, 2021
Project endMarch 31, 2026
Funding year2025
Award (this year)$383,908
NIH project number5R37CA249707-05
Project IDNIH-11057727 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are young adults aged 18-24 who use both nicotine and cannabis products.

Less likely to help

Patients who do not use nicotine or cannabis products may not benefit from this research.

What this research studies

This research investigates the patterns and effects of young adults co-using nicotine and cannabis through vaping. By utilizing Ecological Momentary Assessment (EMA), the study captures real-time data on daily usage and its consequences. It also analyzes long-term survey data to identify predictors of co-use and its impact on mental and physical health. The goal is to better understand how these substances interact and affect young people's well-being.

Why it matters

Potential benefit: If successful, this research could lead to improved public health strategies aimed at reducing the risks associated with vaping nicotine and cannabis among young adults.

How similar studies have gone: While there has been research on combustible tobacco and cannabis use, this study's focus on vaping co-use is relatively novel and untested.

Where this research is happening

  • Rand Corporation
    Santa Monica, United States
    Active

Researchers

  • Principal investigator: Dunbar, Michael — Rand Corporation
  • Study coordinator: Dunbar, Michael

Related research

Other NIH-funded projects on the same topics.

  • Helping Parents Prevent Adolescent Vaping: A Longitudinal Study and Experimental Messages

    A study with 12-year-olds’ families aims to understand how parental knowledge and parenting practices influence teens’ nicotine and cannabis vaping, and tests messages to help parents prevent vaping.

    NIH research University of Oklahoma Hlth Sciences Ctr · Oklahoma City, United States · NIH-11344769

  • Chemicals released by vaping cannabis

    This work looks at which chemicals are produced when people vape concentrated cannabis and how different devices and formulations change those emissions, with special attention to risks for young users.

    NIH research Portland State University · Portland, United States · NIH-11324297

  • Investigating the chemicals and toxic emissions from cannabis vaping

    This study is looking at how vaping cannabis affects health, especially for young people, by figuring out what harmful chemicals are released when different types of cannabis and vaporizers are used, so we can better understand the safety of these products.

    NIH research Portland State University · Portland, United States · NIH-11081796

  • How local tobacco and cannabis stores affect teen vaping habits

    This study looks at how having more tobacco and cannabis shops close to homes and schools affects young people's vaping habits, especially if they live in less advantaged neighborhoods, to help create better policies to reduce vaping among teens.

    NIH research University of Southern California · Los Angeles, UNITED STATES · NIH-11054674

  • Investigating the effects of vaping nicotine and cannabis in young people

    This study is looking at how vaping nicotine and cannabis impacts young people aged 12 to 20, to see if it leads to more smoking or if it’s linked to other challenges they might be facing, with the goal of helping to create better health strategies for them.

    NIH research University of Southern California · Los Angeles, UNITED STATES · NIH-10926856

  • Hemp-derived CBD for reducing cannabis use in high-THC concentrate users

    A randomized, placebo-controlled trial tests whether hemp-derived CBD can help adults who mainly use high-potency cannabis concentrates reduce their cannabis use.

    NIH research University of Colorado · Boulder, UNITED STATES · NIH-11567759

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.