Understanding how YES1 affects triple negative breast cancer
Discovering the role of YES1 in triple negative breast cancer
This study is looking at a protein called YES1 to see how it helps triple negative breast cancer grow, with the hope of finding new ways to treat this tough type of cancer that could lead to better therapies for patients.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Cleveland Clinic Lerner Com-Cwru NIH-funded |
| Lab location | 1 site (Cleveland, United States) |
| Project ID | NIH-11007271 on NIH RePORTER |
What this research studies
This research investigates the role of a protein called YES1 in triple negative breast cancer (TNBC), a particularly aggressive form of breast cancer with limited treatment options. The study aims to understand how YES1 contributes to the growth and survival of TNBC cells, especially in relation to another protein called Epidermal Growth Factor Receptor (EGFR). By exploring the unique functions of YES1, the researchers hope to identify new vulnerabilities in TNBC that could lead to improved treatment strategies. Patients may benefit from insights that could lead to more effective therapies targeting YES1 and its pathways.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with triple negative breast cancer.
Not a fit: Patients with other types of breast cancer or those without a cancer diagnosis may not receive benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatment options for patients with triple negative breast cancer.
How similar studies have performed: Other research has shown promising results in targeting similar pathways in cancer treatment, suggesting potential for success in this approach.
Where this research is happening
Cleveland, United States
- Cleveland Clinic Lerner Com-Cwru — Cleveland, United States (Active)
Researchers
- Principal investigator: Keri, Ruth a. — Cleveland Clinic Lerner Com-Cwru
- Study coordinator: Keri, Ruth a.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.