Understanding how yeast cells divide and maintain genetic integrity
Saccharomyces cerevisiae microtubule and kinetochore dynamics
This study looks at how tiny structures in yeast cells help make sure chromosomes are divided correctly during cell division, which is important for keeping our genes healthy and could help prevent issues like cancer and birth defects.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California Berkeley NIH-funded |
| Lab location | 1 site (Berkeley, United States) |
| Project ID | NIH-11123087 on NIH RePORTER |
What this research studies
This research investigates the dynamics of microtubules and kinetochores in yeast cells, which are crucial for accurate chromosome segregation during cell division. By examining how these structures interact and function, the study aims to uncover the mechanisms that ensure genomic integrity and prevent conditions such as cancer and birth defects. The approach involves advanced biochemical assays to analyze the behavior of proteins involved in these processes. Patients may benefit from insights gained that could lead to improved cancer prevention strategies.
Who could benefit from this research
Good fit: Ideal candidates for participation or benefit from this research include individuals with a family history of cancer or congenital abnormalities.
Not a fit: Patients with conditions unrelated to cell division or genetic integrity may not receive direct benefits from this research.
Why it matters
Potential benefit: If successful, this research could lead to new strategies for preventing cancer and congenital defects by enhancing our understanding of cell division.
How similar studies have performed: Other research has shown success in understanding cell division mechanisms, suggesting that this approach could yield valuable insights.
Where this research is happening
Berkeley, United States
- University of California Berkeley — Berkeley, United States (Active)
Researchers
- Principal investigator: Barnes, Georjana — University of California Berkeley
- Study coordinator: Barnes, Georjana
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.