Understanding how yeast adapt to different environments and pressures
Official title: Examining the conditionality and time dynamics of evolutionary constraint in yeast
Funded at Stanford University · NIH-10995985 · Data updated 2026-11-12
This study looks at how yeast can adapt to challenges like drugs and environmental changes, which can help us understand how similar processes work in harmful organisms like bacteria and cancer cells, ultimately guiding us in fighting drug resistance.
Quick facts
| Grant type | Fellowship grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Stanford University NIH-funded |
| Lab location | 1 site (Stanford, United States) |
| Project start | September 1, 2024 |
| Project end | August 31, 2026 |
| Funding year | 2024 |
| Award (this year) | $73,828 |
| NIH project number | 1F32GM155990-01 |
| Project ID | NIH-10995985 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for benefiting from this research include individuals affected by drug-resistant infections or cancers.
✕Less likely to help
Patients with conditions unrelated to evolutionary biology or drug resistance may not receive direct benefits from this research.
What this research studies
This research investigates how evolutionary constraints affect the ability of yeast to adapt to various selective pressures, such as drugs and environmental changes. By using advanced microbial experimental evolution techniques, the study aims to measure the fitness effects of mutations in different settings. This approach will help clarify the complex processes that influence how organisms, including those relevant to human health like pathogens and cancers, evolve over time. The findings could provide insights into the adaptability of these organisms and inform strategies for managing drug resistance.
Why it matters
Potential benefit: If successful, this research could lead to improved strategies for combating drug resistance in pathogens and cancers.
How similar studies have gone: Other research has shown success in using experimental evolution methods to understand adaptation in microbial populations, indicating that this approach is promising.
Where this research is happening
-
Stanford University
Stanford, United States Active
Researchers
- Principal investigator: Visher, Elisa — Stanford University
- Study coordinator: Visher, Elisa
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.