Understanding how wounds are detected and healed in animals
Chemical and Physical Mechanisms of Wound Detection
This study is looking at how animals, like zebrafish, notice when they get hurt and start to heal, with the hope that understanding this process better can help improve treatments for wounds that don’t heal well.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Sloan-Kettering Inst Can Research NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project ID | NIH-11076713 on NIH RePORTER |
What this research studies
This research investigates the mechanisms by which animals detect and respond to injuries, focusing on the initial signals that trigger wound healing. Using live zebrafish, which have similar wound responses to mammals, the study employs advanced imaging techniques to observe how chemical and physical signals are transmitted to cells involved in healing. The research aims to fill a critical gap in knowledge about wound detection, which could lead to better treatments for conditions like poorly healing wounds and chronic inflammation.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals suffering from acute or chronic wounds, infections, or conditions related to impaired wound healing.
Not a fit: Patients with non-healing wounds due to unrelated systemic conditions or those not involving the mechanisms studied may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved therapies for wound healing and management of chronic conditions related to injury.
How similar studies have performed: Previous research has shown promise in understanding wound healing mechanisms, but this specific approach using zebrafish is relatively novel.
Where this research is happening
New York, United States
- Sloan-Kettering Inst Can Research — New York, United States (Active)
Researchers
- Principal investigator: Niethammer, Philipp Michael — Sloan-Kettering Inst Can Research
- Study coordinator: Niethammer, Philipp Michael
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.