Understanding how Wnt signaling helps guide nerve growth and repair
Characterizing Wnt Signaling Pathways in Axon Guidance
['FUNDING_R37'] · UNIVERSITY OF CALIFORNIA, SAN DIEGO · NIH-11081643
This study is looking at how certain signals in the body help nerve cells grow and connect properly, which could lead to new ways to help people recover from spinal cord injuries.
Quick facts
| Phase | ['FUNDING_R37'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF CALIFORNIA, SAN DIEGO (nih funded) |
| Locations | 1 site (LA JOLLA, UNITED STATES) |
| Trial ID | NIH-11081643 on ClinicalTrials.gov |
What this research studies
This research investigates the role of Wnt signaling pathways in guiding the growth of axons, which are crucial for forming neural circuits. It aims to uncover how these pathways influence the direction of axon growth during development and their potential in promoting recovery after spinal cord injuries. By exploring the interactions between different signaling pathways, the research seeks to provide insights into the mechanisms that govern nerve regeneration and synapse formation. This could lead to new strategies for repairing damaged neural circuits in adults.
Who could benefit from this research
Good fit: Ideal candidates for this research are adults who have experienced spinal cord injuries or are affected by neurodegenerative disorders.
Not a fit: Patients with conditions unrelated to nerve growth or regeneration may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved therapies for nerve injuries and neurodegenerative diseases, enhancing recovery and restoring function.
How similar studies have performed: Previous research has shown promising results in understanding axon guidance and regeneration, indicating that this approach has potential for significant advancements.
Where this research is happening
LA JOLLA, UNITED STATES
- UNIVERSITY OF CALIFORNIA, SAN DIEGO — LA JOLLA, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: ZOU, YIMIN — UNIVERSITY OF CALIFORNIA, SAN DIEGO
- Study coordinator: ZOU, YIMIN
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.