Understanding how Wnt signaling affects tendon healing and maturation
Official title: Investigating the Role of Wnt Signaling in the Mechanical Maturation of Tendon
Funded at Massachusetts General Hospital · NIH-11068084 · Data updated 2026-11-12
This study is looking at how tendons heal and grow stronger after an injury, focusing on a specific process in the body, to find better ways to help people recover from tendon injuries and improve their everyday activities.
Quick facts
| Grant type | Fellowship grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Massachusetts General Hospital NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project start | May 1, 2025 |
| Project end | April 30, 2028 |
| Funding year | 2025 |
| Award (this year) | $79,456 |
| NIH project number | 1F32AR085460-01 |
| Project ID | NIH-11068084 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are adults with tendon injuries, particularly those affecting the Achilles tendon.
✕Less likely to help
Patients with tendon injuries who are under 21 years old may not benefit from this research.
What this research studies
This research investigates the biological mechanisms involved in the healing and maturation of tendons, particularly focusing on the role of Wnt signaling. Tendon injuries can severely impact daily activities due to their poor healing capabilities, often resulting in scar tissue that is less effective than healthy tendon tissue. By studying the cellular and molecular processes that govern tendon maturation, the research aims to identify new strategies for improving tendon structure and function after injury. This could lead to more effective treatments for patients suffering from tendon injuries.
Why it matters
Potential benefit: If successful, this research could lead to improved treatments for tendon injuries, enhancing recovery and quality of life for patients.
How similar studies have gone: Other research has shown promise in understanding tendon healing mechanisms, but this specific focus on Wnt signaling is relatively novel.
Where this research is happening
-
Massachusetts General Hospital
Boston, United States Active
Researchers
- Principal investigator: Peterson, Benjamin — Massachusetts General Hospital
- Study coordinator: Peterson, Benjamin
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.