Understanding how where you live affects lung transplant outcomes
Official title: A place-based approach to geographic disparities in lung transplant
Funded at Cleveland Clinic Lerner Com-Cwru · NIH-11109417 · Data updated 2026-11-12
This project explores how a patient's living environment might affect their lung health and survival after a lung transplant.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Cleveland Clinic Lerner Com-Cwru NIH-funded |
| Lab location | 1 site (Cleveland, United States) |
| Project start | August 1, 2023 |
| Project end | May 31, 2028 |
| Funding year | 2025 |
| Award (this year) | $685,365 |
| NIH project number | 5R01HL164660-03 |
| Project ID | NIH-11109417 on NIH RePORTER |
Who could benefit from this research
✓Could help
This research focuses on understanding factors affecting individuals who have already received a lung transplant.
✕Less likely to help
Patients who have not undergone a lung transplant would not directly benefit from this specific research.
What this research studies
This project aims to understand why some lung transplant patients experience faster lung function decline and shorter survival, especially noting differences based on where they live. Researchers believe that factors in a patient's social and environmental surroundings, or "place-based factors," could be causing small, unnoticed injuries to the transplanted lungs. By using advanced mapping and data tools, they plan to link patient information from multiple transplant centers to specific geographic areas. This will help them uncover how these environmental factors contribute to the challenges faced by lung transplant recipients. The goal is to better predict risks and develop new ways to support patients after their transplant.
Why it matters
Potential benefit: If successful, this work could lead to better ways to predict risks for lung transplant patients and develop new strategies to improve their long-term health and survival.
How similar studies have gone: This approach to linking geographic factors with lung transplant outcomes is a novel area of focus, building on existing knowledge of transplant survival disparities.
Where this research is happening
-
Cleveland Clinic Lerner Com-Cwru
Cleveland, United States Active
Researchers
- Principal investigator: Tsuang, Wayne M — Cleveland Clinic Lerner Com-Cwru
- Study coordinator: Tsuang, Wayne M
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.