NIH-funded research R03 grant

Understanding how wheelchair use affects boys and girls differently during growth

Official title: Quantifying Sex-Specific Musculoskeletal Adaptations to Wheelchair Use in Childhood and Adolescence

Funded at University of Illinois at Urbana-Champaign · NIH-10816783 · Data updated 2026-11-12

This study looks at how using a wheelchair affects the muscles and bones of boys and girls, especially focusing on why girls might experience more shoulder pain as they grow up, so we can better understand their needs and help them stay healthy.

Quick facts

Grant typeR03 grant
Study typeNIH-funded research
Funding institutionUniversity of Illinois at Urbana-Champaign
NIH-funded
Lab location1 site (Champaign, United States)
Project startAugust 1, 2024
Project endJuly 31, 2026
Funding year2024
Award (this year)$301,304
NIH project number1R03HD114181-01
Project IDNIH-10816783 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are children and adolescents aged 12 to 20 who use manual wheelchairs.

Less likely to help

Patients who do not use wheelchairs or are outside the age range of 12 to 20 may not benefit from this research.

What this research studies

This research investigates the impact of wheelchair use on musculoskeletal health in children and adolescents, focusing on the differences between sexes. It aims to quantify how boys and girls adapt physically to the demands of using a wheelchair, particularly regarding shoulder pain and related conditions. By examining these adaptations, the study seeks to identify the reasons behind the higher incidence of pain in female wheelchair users as they transition into adulthood. The methodology includes assessing muscle and bone growth rates and the mechanical demands placed on the upper body during wheelchair use.

Why it matters

Potential benefit: If successful, this research could lead to improved guidelines for preventing shoulder pain and enhancing the quality of life for young wheelchair users.

How similar studies have gone: Previous research has indicated that understanding sex-specific adaptations in physical activity can lead to better health outcomes, suggesting potential success for this approach.

Where this research is happening

  • University of Illinois at Urbana-Champaign
    Champaign, United States
    Active

Researchers

  • Principal investigator: Leonardis, Joshua — University of Illinois at Urbana-Champaign
  • Study coordinator: Leonardis, Joshua

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.