Understanding how West Nile Virus spreads through mosquitoes
Hologenomic basis of WNV vector competence in Culex tarsalis
This study looks at how the West Nile Virus spreads among certain mosquitoes, especially the Culex tarsalis, by exploring their genetics and the tiny organisms living with them, which could help us find better ways to prevent and control outbreaks of the virus.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Pennsylvania State University, the NIH-funded |
| Lab location | 1 site (University Park, United States) |
| Project ID | NIH-10894326 on NIH RePORTER |
What this research studies
This research investigates the factors that influence how the West Nile Virus (WNV) spreads among mosquito populations, particularly focusing on the Culex tarsalis species. By examining the genetic makeup of these mosquitoes and their associated microorganisms, the study aims to identify key elements that contribute to the mosquitoes' ability to transmit the virus. The findings could lead to better risk assessment strategies and targeted control efforts to manage WNV outbreaks. This research combines genetic analysis with ecological studies to provide a comprehensive understanding of pathogen dynamics.
Who could benefit from this research
Good fit: Ideal candidates for participation or benefit from this research include individuals living in areas where West Nile Virus is prevalent and those at higher risk of infection due to environmental exposure.
Not a fit: Patients who live in regions where West Nile Virus is not present or who are not at risk of mosquito bites may not receive any benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved strategies for controlling the spread of West Nile Virus, ultimately reducing the incidence of disease in humans.
How similar studies have performed: Previous research has shown success in understanding vector competence and pathogen dynamics in other mosquito species, indicating that this approach has potential for yielding valuable insights.
Where this research is happening
University Park, United States
- Pennsylvania State University, the — University Park, United States (Active)
Researchers
- Principal investigator: Rasgon, Jason L — Pennsylvania State University, the
- Study coordinator: Rasgon, Jason L
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.