Understanding how well vaccines work against respiratory viruses in real-world settings

RFA-IP-22-004, Multidisciplinary Approach to Understanding Vaccine Efficacy and Transmission of Viral Respiratory Tract Infections in the Real World

['FUNDING_U01'] · WASHINGTON UNIVERSITY · NIH-10909767

This study is looking at how well flu and COVID-19 vaccines work for people with respiratory infections, and it’s for anyone who wants to understand more about vaccine protection in real-life situations.

Quick facts

Phase['FUNDING_U01']
Study typeNih_funding
SexAll
SponsorWASHINGTON UNIVERSITY (nih funded)
Locations1 site (SAINT LOUIS, UNITED STATES)
Trial IDNIH-10909767 on ClinicalTrials.gov

What this research studies

This research investigates the effectiveness of vaccines against influenza and SARS-CoV-2 in patients experiencing respiratory infections. By employing a multidisciplinary approach, the study aims to recruit a diverse group of ambulatory patients using automated alerts and advanced data collection methods. The research team, composed of experts from various fields, will analyze samples and data to assess how well these vaccines protect against these viral infections in everyday situations. The findings will help inform public health strategies and improve vaccine deployment.

Who could benefit from this research

Good fit: Ideal candidates for participation include individuals experiencing acute respiratory illnesses who are seeking outpatient care.

Not a fit: Patients who are not currently experiencing respiratory infections or those who have already been vaccinated may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved vaccine strategies that enhance protection against respiratory viruses for the general population.

How similar studies have performed: Previous research has successfully utilized similar multidisciplinary approaches to assess vaccine effectiveness, indicating a promising potential for this study.

Where this research is happening

SAINT LOUIS, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.