Understanding how walking and thinking are connected in Alzheimer's disease
Official title: Neural Correlates of Cognitive-Motor Interactions in ADRD Gait
Funded at University of Florida · NIH-10977613 · Data updated 2026-11-12
This study is looking at how walking and thinking are connected in older adults, especially those with Alzheimer's, to see if changes in how they walk can help spot early signs of memory problems, which could lead to new ways to help those at risk.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Florida NIH-funded |
| Lab location | 1 site (Gainesville, United States) |
| Project start | September 18, 2024 |
| Project end | August 31, 2029 |
| Funding year | 2024 |
| Award (this year) | $804,795 |
| NIH project number | 1R01AG089050-01 |
| Project ID | NIH-10977613 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include older adults experiencing mobility issues or early signs of cognitive decline.
✕Less likely to help
Patients with advanced Alzheimer's disease or those without any mobility or cognitive concerns may not benefit from this research.
What this research studies
This research investigates the neural mechanisms that link gait (walking) and cognitive function in older adults, particularly those with Alzheimer's disease and related dementias. By examining how mobility declines can serve as early indicators of cognitive impairment, the study aims to identify potential biomarkers for Alzheimer's disease. The research team, composed of experts in aging and neuroscience, will explore the role of vestibular function and its impact on both gait and cognition. This could lead to new early interventions for individuals at risk of cognitive decline.
Why it matters
Potential benefit: If successful, this research could provide early detection methods for Alzheimer's disease, allowing for timely interventions.
How similar studies have gone: Previous research has shown promising results in understanding the relationship between mobility and cognitive decline, suggesting that this approach could yield valuable insights.
Where this research is happening
-
University of Florida
Gainesville, United States Active
Researchers
- Principal investigator: Seidler, Rachael D — University of Florida
- Study coordinator: Seidler, Rachael D
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.