NIH-funded research R01 grant

Understanding how visual pigments work and their role in eye diseases

Official title: Chemical Biology of the Visual Pigments

Funded at University of California-Irvine · NIH-11054551 · Data updated 2026-11-12

This study is looking at how the special pigments in our eyes work and how they can be affected by eye diseases, with the goal of finding new ways to improve treatments for vision problems.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of California-Irvine
NIH-funded
Lab location1 site (Irvine, United States)
Project startMarch 1, 2023
Project endFebruary 28, 2027
Funding year2025
Award (this year)$449,125
NIH project number5R01EY034519-03
Project IDNIH-11054551 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research include individuals with retinal diseases or those experiencing vision problems related to visual pigment dysfunction.

Less likely to help

Patients with non-retinal vision issues or those without any visual impairment may not benefit from this research.

What this research studies

This research investigates the structure and function of visual pigments, which are crucial for human vision and are impacted by retinal diseases. The team will explore how these pigments respond to light and the biochemical processes that follow, using advanced techniques to address gaps in current knowledge. By studying the interactions of visual pigments and potential therapeutic agents, the research aims to uncover new insights that could lead to better treatments for vision-related conditions.

Why it matters

Potential benefit: If successful, this research could lead to improved treatments for retinal diseases, enhancing vision and quality of life for affected patients.

How similar studies have gone: Previous research has shown promise in understanding visual pigments and their role in vision, suggesting that this approach could yield valuable insights.

Where this research is happening

  • University of California-Irvine
    Irvine, United States
    Active

Researchers

  • Principal investigator: Kiser, Philip David — University of California-Irvine
  • Study coordinator: Kiser, Philip David

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.