Understanding how vision loss affects brain function and behavior

Characterization of Multiple Factors in Training and Plasticity in Central Vision Loss

NIH-funded research University of Alabama at Birmingham · NIH-10798345

This study looks at how losing central vision from macular degeneration affects everyday tasks like reading and recognizing faces, and it aims to understand how the brain adapts to these changes by simulating vision loss in healthy people.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Alabama at Birmingham NIH-funded
Lab location1 site (Birmingham, United States)
Project IDNIH-10798345 on NIH RePORTER

What this research studies

This research investigates how central vision loss, particularly from macular degeneration, impacts daily activities like reading and recognizing faces. By simulating vision loss in healthy individuals, the study examines how the brain adapts and changes its activity patterns in response to altered visual experiences. Using advanced eye-tracking technology, researchers aim to uncover the complex interactions between visual processes and brain systems, ultimately seeking to improve perceptual learning for those affected by vision loss.

Who could benefit from this research

Good fit: Ideal candidates for this research include adults experiencing central vision loss due to conditions like macular degeneration.

Not a fit: Patients with vision loss from causes other than macular degeneration may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to new strategies for helping patients with vision loss improve their daily functioning and quality of life.

How similar studies have performed: Previous research has shown promising results in understanding brain plasticity and visual adaptation, indicating potential for success in this approach.

Where this research is happening

Birmingham, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.