Understanding how viruses jump between different species

Unravelling the mechanisms of virus host species jump

NIH-funded research Arizona State University-Tempe Campus · NIH-11117739

This study is looking at how viruses, like the ones that cause COVID-19 and monkeypox, can jump from one animal species to another, and it’s for anyone interested in understanding how we can better prevent future outbreaks.

Quick facts

Grant typeR21 grant
Study typeNIH-funded research
Funding institutionArizona State University-Tempe Campus NIH-funded
Lab location1 site (Tempe, United States)
Project IDNIH-11117739 on NIH RePORTER

What this research studies

This research investigates the mechanisms that allow viruses to cross from one species to another, which is crucial for understanding outbreaks of diseases like COVID-19 and monkeypox. By studying the evolution of the Myxoma virus, which has shown different effects on its natural and new hosts, researchers aim to uncover the genetic changes that facilitate these species jumps. The project will analyze viral genomes and their interactions with host species to identify key factors that contribute to viral spillovers. This knowledge could help in predicting and preventing future outbreaks.

Who could benefit from this research

Good fit: Ideal candidates for benefiting from this research include individuals at risk of zoonotic diseases, particularly those in close contact with animals.

Not a fit: Patients who are not at risk of zoonotic diseases or do not have exposure to animal populations may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to better strategies for preventing viral outbreaks that affect human health.

How similar studies have performed: Previous research has shown success in understanding viral evolution and spillover events, indicating that this approach has potential for significant findings.

Where this research is happening

Tempe, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.