Understanding how viruses assemble and interact with their hosts
Phages as Lenses to Study Virus Assembly and Virus: Host Interactions
['FUNDING_OTHER'] · UNIVERSITY OF CONNECTICUT STORRS · NIH-11011656
This study is looking at how certain viruses, like bacteriophage P22, put themselves together, which could help scientists find new ways to create antiviral medicines by understanding how to stop viruses from forming properly.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF CONNECTICUT STORRS (nih funded) |
| Locations | 1 site (STORRS-MANSFIELD, UNITED STATES) |
| Trial ID | NIH-11011656 on ClinicalTrials.gov |
What this research studies
This research investigates the assembly process of viral capsids, specifically using bacteriophage P22 as a model. By examining the interactions between various proteins involved in the capsid assembly, the study aims to uncover the mechanisms that dictate how these proteins adopt the correct shapes and structures. This knowledge could lead to the development of new antiviral drugs by providing insights into how to disrupt viral assembly. The research employs both in vitro and in vivo techniques to mimic complex biological processes.
Who could benefit from this research
Good fit: Ideal candidates for this research would include individuals with viral infections that could potentially be treated with new antiviral agents.
Not a fit: Patients with non-viral infections or conditions unrelated to viral mechanisms may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to the development of novel antiviral therapies that effectively target viral assembly processes.
How similar studies have performed: Previous research has shown promise in understanding viral assembly mechanisms, suggesting that this approach could yield significant advancements in antiviral drug development.
Where this research is happening
STORRS-MANSFIELD, UNITED STATES
- UNIVERSITY OF CONNECTICUT STORRS — STORRS-MANSFIELD, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: TESCHKE, CAROLYN M — UNIVERSITY OF CONNECTICUT STORRS
- Study coordinator: TESCHKE, CAROLYN M
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.