Understanding how viruses and bacteria interact during infections
Consequences of Direct Viral-Bacterial Interactions
This study is looking at how the flu virus works together with a common bacteria that can cause pneumonia, to better understand how they can make respiratory illnesses worse, with the hope of finding new ways to prevent and treat these infections.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | St. Jude Children's Research Hospital NIH-funded |
| Lab location | 1 site (Memphis, United States) |
| Project ID | NIH-11013322 on NIH RePORTER |
What this research studies
This research investigates the interactions between the influenza A virus and Streptococcus pneumoniae, a common bacterium that can cause pneumonia. It explores how the virus binds to the bacteria, enhancing their ability to adhere and spread within the body. By studying these interactions, the research aims to uncover the mechanisms that facilitate co-infections, which can lead to more severe respiratory diseases. The findings could help identify new strategies for preventing and treating infections caused by these pathogens.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals who are at risk for respiratory infections, particularly those with a history of influenza or pneumonia.
Not a fit: Patients who do not have respiratory infections or are not at risk for such infections may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved prevention and treatment strategies for respiratory infections caused by viruses and bacteria.
How similar studies have performed: Previous research has shown that understanding the interactions between viruses and bacteria can lead to significant advancements in treatment, indicating that this approach has potential for success.
Where this research is happening
Memphis, United States
- St. Jude Children's Research Hospital — Memphis, United States (Active)
Researchers
- Principal investigator: Rosch, Jason W. — St. Jude Children's Research Hospital
- Study coordinator: Rosch, Jason W.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.