Understanding how viruses and allergens affect immune responses in chronic lung disease
Viral and allergen-driven immunity in chronic lung disease
['FUNDING_OTHER'] · UNIVERSITY OF MICHIGAN AT ANN ARBOR · NIH-11009053
This study is looking at how viruses, allergens, and the immune system work together in people with chronic lung diseases like asthma, especially those with severe allergies, to find new ways to help improve their breathing and overall health.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF MICHIGAN AT ANN ARBOR (nih funded) |
| Locations | 1 site (ANN ARBOR, UNITED STATES) |
| Trial ID | NIH-11009053 on ClinicalTrials.gov |
What this research studies
This research investigates the complex interactions between viral infections, allergens, and the immune system in patients with chronic lung diseases like asthma. It focuses on how these factors contribute to airway inflammation and structural changes, particularly in severe allergic asthma. The study employs advanced techniques to analyze immune cell behavior and metabolism, aiming to identify potential therapeutic targets that could improve patient outcomes. By understanding these mechanisms, the research seeks to develop new strategies for managing chronic lung conditions.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals with chronic lung diseases, especially those experiencing severe allergic asthma.
Not a fit: Patients with mild asthma or those whose conditions are not driven by viral infections or allergens may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved treatments for patients suffering from chronic lung diseases, particularly those with severe asthma.
How similar studies have performed: Previous research has shown promise in understanding immune responses in chronic lung diseases, suggesting that this approach could yield valuable insights and advancements.
Where this research is happening
ANN ARBOR, UNITED STATES
- UNIVERSITY OF MICHIGAN AT ANN ARBOR — ANN ARBOR, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: LUKACS, NICHOLAS W — UNIVERSITY OF MICHIGAN AT ANN ARBOR
- Study coordinator: LUKACS, NICHOLAS W
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Airway Disease