Understanding how viral RNA triggers immune responses during flavivirus infections
Official title: Identity and Accessibility of Immunostimulatory Viral RNAs During Flavivirus Infection
Funded at University of Washington · NIH-11007189 · Data updated 2026-11-12
This study is looking at how our body's natural defenses kick in when we're infected with viruses like the West Nile virus, focusing on the virus's genetic material to find out what triggers our immune response, which could help improve treatments for these infections.
Quick facts
| Grant type | Fellowship grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Washington NIH-funded |
| Lab location | 1 site (Seattle, United States) |
| Project start | December 1, 2023 |
| Project end | November 30, 2025 |
| Funding year | 2025 |
| Award (this year) | $78,892 |
| NIH project number | 5F32AI176736-02 |
| Project ID | NIH-11007189 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals who have been infected with flaviviruses, particularly those showing symptoms of infection.
✕Less likely to help
Patients who are not infected with flaviviruses or those with unrelated health conditions may not benefit from this research.
What this research studies
This research investigates the molecular mechanisms that activate the innate immune response when the body is infected with flaviviruses, such as the West Nile virus. By focusing on the viral RNA, the study aims to identify specific features that stimulate immune activation and how these viral components interact within infected cells. The research employs advanced techniques to analyze viral RNA and its role in immune signaling pathways, which could lead to better understanding and treatment of flavivirus infections.
Why it matters
Potential benefit: If successful, this research could lead to improved strategies for preventing and treating flavivirus infections, potentially reducing the global disease burden.
How similar studies have gone: Previous research has shown promising results in understanding immune responses to viral infections, indicating that this approach could yield valuable insights.
Where this research is happening
-
University of Washington
Seattle, United States Active
Researchers
- Principal investigator: Genoyer, Emmanuelle — University of Washington
- Study coordinator: Genoyer, Emmanuelle
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.