Understanding how vasopressin affects social learning in the brain
Dissecting the role of vasopressin in regulating the critical period for social reward learning
This study is looking at how a hormone called vasopressin affects the way we learn about social rewards as we grow up, which could help us find new ways to support people with social challenges.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Johns Hopkins University NIH-funded |
| Lab location | 1 site (Baltimore, United States) |
| Project ID | NIH-10757353 on NIH RePORTER |
What this research studies
This research investigates the role of vasopressin, a hormone, in shaping social reward learning during critical developmental periods. By examining how vasopressin signaling influences brain circuits, particularly in the ventral pallidum, the study aims to uncover the molecular mechanisms that govern social brain development. The researchers will utilize advanced techniques to map neuronal projections and assess synaptic changes in response to vasopressin across different developmental stages. This work could lead to new therapeutic strategies for neurodevelopmental disorders that involve social impairments.
Who could benefit from this research
Good fit: Ideal candidates for this research are adults over 21 years old who may have neurodevelopmental disorders or social impairments.
Not a fit: Patients who do not have social impairments or neurodevelopmental disorders may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved treatments for individuals with neurodevelopmental disorders characterized by social difficulties.
How similar studies have performed: Previous research has shown promising results in understanding the role of vasopressin in social behavior, suggesting that this approach could yield valuable insights.
Where this research is happening
Baltimore, United States
- Johns Hopkins University — Baltimore, United States (Active)
Researchers
- Principal investigator: Dolen, Gul — Johns Hopkins University
- Study coordinator: Dolen, Gul
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.