Understanding how vascular leak affects outcomes in idiopathic pulmonary fibrosis
Vascular Leak and Outcomes in IPF
This study is looking at how ongoing lung damage affects the progression of idiopathic pulmonary fibrosis (IPF) in patients, using advanced MRI technology to help predict how quickly the disease might get worse, which could lead to more tailored treatments and better timing for lung transplants.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Massachusetts General Hospital NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project ID | NIH-10818404 on NIH RePORTER |
What this research studies
This research investigates idiopathic pulmonary fibrosis (IPF), a serious lung disease that varies greatly among patients. It aims to identify how ongoing lung injury, particularly vascular leak, influences disease progression and patient outcomes. By using advanced MRI techniques, the study seeks to develop methods for predicting how quickly the disease may worsen in individual patients. This could lead to more personalized treatment plans and better timing for lung transplantation evaluations.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with idiopathic pulmonary fibrosis who are experiencing varying rates of disease progression.
Not a fit: Patients with other forms of lung disease or those not diagnosed with idiopathic pulmonary fibrosis may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could enable more accurate predictions of disease progression in IPF patients, leading to improved treatment strategies and outcomes.
How similar studies have performed: Previous research has shown that understanding vascular leak and lung injury can provide insights into disease progression in pulmonary conditions, suggesting potential for success in this approach.
Where this research is happening
Boston, United States
- Massachusetts General Hospital — Boston, United States (Active)
Researchers
- Principal investigator: Montesi, Sydney — Massachusetts General Hospital
- Study coordinator: Montesi, Sydney
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.