Understanding how various factors affect the risk of Alzheimer's disease and related dementias
Official title: Core D: Cognition, Exposure, and Covariates (CEC) Data Core
Funded at Boston University Medical Campus · NIH-10934712 · Data updated 2026-11-12
This study is looking at how things like drinking alcohol, feeling depressed, taking antidepressants, having trouble with hearing or vision, and being socially isolated might affect the chances of developing Alzheimer's disease and similar conditions, so we can better understand how to prevent them.
Quick facts
| Grant type | P01 program project |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Boston University Medical Campus NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project start | September 15, 2024 |
| Project end | August 31, 2029 |
| Funding year | 2024 |
| Award (this year) | $697,534 |
| NIH project number | 1P01AG082653-01A1 |
| Project ID | NIH-10934712 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include individuals at risk for Alzheimer's disease, particularly those with a history of alcohol use, depression, or social isolation.
✕Less likely to help
Patients who are not at risk for Alzheimer's disease or related dementias may not receive any benefit from this research.
What this research studies
This research focuses on identifying how four key risk factors—alcohol use, depression and antidepressant medications, treatment of hearing and vision impairments, and social isolation—impact the risk of developing Alzheimer's disease and related dementias. By utilizing multiple data sources, the project aims to create comprehensive analytic datasets that will help researchers better understand these relationships. The Cognition, Exposure, and Covariates Data Core will facilitate data cleaning and coding, ensuring consistency across various research teams involved in the project. This collaborative approach aims to enhance the quality of data and findings related to Alzheimer's disease prevention.
Why it matters
Potential benefit: If successful, this research could lead to improved strategies for preventing Alzheimer's disease and related dementias by identifying modifiable risk factors.
How similar studies have gone: Previous research has shown promise in understanding the impact of lifestyle factors on Alzheimer's disease risk, making this approach both relevant and potentially impactful.
Where this research is happening
-
Boston University Medical Campus
Boston, United States Active
Researchers
- Principal investigator: Casaletto, Kaitlin B — Boston University Medical Campus
- Study coordinator: Casaletto, Kaitlin B
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.