Understanding how various factors affect liver disease outcomes in different racial and ethnic groups
Official title: Determining the Influence of Clinicodemographic, Biologic and SDOH Factors in Racial and Ethnic Disparities in the Prognosis of Alcohol-Associated Liver Disease
Funded at Ut Southwestern Medical Center · NIH-10930163 · Data updated 2026-11-12
This study is looking at how different factors like age, health background, and social situations affect the outcomes of alcohol-related liver disease, especially for Hispanic and American Indian communities, and it hopes to gather information from patients to help improve treatment in the future.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Ut Southwestern Medical Center NIH-funded |
| Lab location | 1 site (Dallas, United States) |
| Project start | September 20, 2023 |
| Project end | August 31, 2028 |
| Funding year | 2024 |
| Award (this year) | $193,288 |
| NIH project number | 5K23AA031310-02 |
| Project ID | NIH-10930163 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include individuals from Hispanic and American Indian backgrounds who are diagnosed with alcohol-associated liver disease.
✕Less likely to help
Patients who do not have alcohol-associated liver disease or those from racial and ethnic groups not represented in the study may not receive benefits from this research.
What this research studies
This research investigates the impact of various factors, including demographic, biological, and social determinants of health, on the prognosis of alcohol-associated liver disease (ALD) among different racial and ethnic groups. The study aims to identify how these factors contribute to disparities in morbidity and mortality, particularly focusing on Hispanic and American Indian populations. By analyzing genetic influences and barriers to care, the research seeks to provide a more comprehensive understanding of ALD's natural history and prognosis. Patients may be involved in providing data that will help clarify these relationships and improve future treatment approaches.
Why it matters
Potential benefit: If successful, this research could lead to tailored treatment strategies that improve outcomes for patients with alcohol-associated liver disease, particularly among underrepresented racial and ethnic groups.
How similar studies have gone: While there has been research on alcohol-associated liver disease, this study's focus on the intersection of clinicodemographic, biological, and social factors in diverse populations is relatively novel.
Where this research is happening
-
Ut Southwestern Medical Center
Dallas, United States Active
Researchers
- Principal investigator: Cotter, Thomas Gerard — Ut Southwestern Medical Center
- Study coordinator: Cotter, Thomas Gerard
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.