Understanding how vaping THC affects the body, with and without nicotine
Assessing pharmacokinetic and pharmacodynamic variability of Δ9-tetrahydrocannabinol delivered from vaping products with and without concurrent use of nicotine
This project aims to learn how vaping products that contain THC, sometimes with nicotine, affect people's bodies and behavior.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Roswell Park Cancer Institute Corp NIH-funded |
| Lab location | 1 site (Buffalo, United States) |
| Project ID | NIH-11123233 on NIH RePORTER |
What this research studies
Many people are now using vaping devices for liquids containing THC, but we don't fully understand how these products affect the body. This project will look at how different vaping devices and user habits change the way THC is absorbed and its effects. We will also explore what happens when people vape THC and nicotine at the same time. This will involve studying current THC vapers in both real-world settings using a mobile lab and in a controlled laboratory environment.
Who could benefit from this research
Good fit: Ideal participants would be current vapers of THC-containing liquids who may also use nicotine vaping products.
Not a fit: Individuals who do not vape THC or nicotine would not directly benefit from participating in this specific research.
Why it matters
Potential benefit: This work could lead to a better understanding of the health effects of THC vaping, potentially informing safer use guidelines or public health policies.
How similar studies have performed: While there is existing knowledge on nicotine vaping, this project addresses a gap in understanding the specific effects of THC vaping, especially with concurrent nicotine use.
Where this research is happening
Buffalo, United States
- Roswell Park Cancer Institute Corp — Buffalo, United States (Active)
Researchers
- Principal investigator: Smith, Danielle — Roswell Park Cancer Institute Corp
- Study coordinator: Smith, Danielle
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.