Understanding how vaccines work against respiratory viruses
Official title: Project 1
Funded at Washington University · NIH-10824579 · Data updated 2026-11-12
This study is looking at how well vaccines for respiratory viruses like the flu and COVID-19 help our immune system remember and fight off these illnesses over time, and it's for adults who want to understand how we can make vaccines even better.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Washington University NIH-funded |
| Lab location | 1 site (Saint Louis, United States) |
| Project start | September 4, 2024 |
| Project end | June 30, 2029 |
| Funding year | 2024 |
| Award (this year) | $754,491 |
| NIH project number | 1U19AI181103-01 |
| Project ID | NIH-10824579 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are adults aged 21 and older who have received vaccinations for influenza or SARS-CoV-2.
✕Less likely to help
Patients who have not been vaccinated against these respiratory viruses may not benefit from this research.
What this research studies
This research investigates the immune response generated by vaccines for respiratory viruses like influenza and SARS-CoV-2. By analyzing blood and tissue samples from vaccinated adults, the study aims to uncover how the immune system's memory functions over time and how it can be improved. The researchers will use advanced techniques to track the behavior of immune cells and their responses to vaccination, providing insights that could lead to more effective vaccines. This work is crucial for enhancing the durability and effectiveness of vaccines against rapidly evolving viruses.
Why it matters
Potential benefit: If successful, this research could lead to the development of more effective vaccines that provide longer-lasting protection against respiratory viruses.
How similar studies have gone: Previous research has shown promise in understanding immune responses to vaccines, but this specific approach is innovative and aims to fill critical knowledge gaps.
Where this research is happening
-
Washington University
Saint Louis, United States Active
Researchers
- Principal investigator: Ellebedy, Ali Hassan — Washington University
- Study coordinator: Ellebedy, Ali Hassan
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.