Understanding how vaccines affect respiratory diseases and asthma in young children
Clinical Core: IDEAL shapes vaccine response, susceptibility to respiratory infectious disease and asthma
This study is looking at how vaccines affect the immune system and the risk of respiratory infections and asthma in kids under 11, and it aims to find ways to improve health for young children by understanding their immune responses better.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Boston Children's Hospital NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project ID | NIH-11051824 on NIH RePORTER |
What this research studies
This research investigates how vaccines influence the immune response and susceptibility to respiratory infections and asthma in children, particularly those under 11 years old. By analyzing clinical samples from various early childhood cohorts, the study aims to identify specific immune signatures and biomarkers associated with vaccine responses and respiratory health. The research will also recruit new infants to gather additional data, which will help in developing targeted interventions for improving health outcomes in young children.
Who could benefit from this research
Good fit: Ideal candidates for this research are children aged 0 to 11 years, particularly those with a history of respiratory infections or asthma.
Not a fit: Patients outside the age range of 0 to 11 years or those without respiratory issues may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved vaccine strategies and treatments for respiratory diseases and asthma in children.
How similar studies have performed: Previous research has shown promise in understanding vaccine responses and respiratory health in children, indicating that this approach could yield valuable insights.
Where this research is happening
Boston, United States
- Boston Children's Hospital — Boston, United States (Active)
Researchers
- Principal investigator: Pichichero, Michael E — Boston Children's Hospital
- Study coordinator: Pichichero, Michael E
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.