NIH-funded research R21 grant

Understanding how uterine glycogen affects pregnancy success

Official title: The Role of Uterine Glycogen in Establishing a Successful Pregnancy

Funded at University of Illinois at Urbana-Champaign · NIH-10725894 · Data updated 2026-11-12

This study is looking at how the sugar stored in the uterus helps with getting pregnant and supporting a healthy embryo, which could lead to better fertility treatments for those trying to conceive.

Quick facts

Grant typeR21 grant
Study typeNIH-funded research
Funding institutionUniversity of Illinois at Urbana-Champaign
NIH-funded
Lab location1 site (Champaign, United States)
Project startAugust 1, 2023
Project endJuly 31, 2025
Funding year2023
Award (this year)$327,507
NIH project number1R21HD112772-01
Project IDNIH-10725894 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are women experiencing infertility or recurrent pregnancy loss.

Less likely to help

Patients who are not seeking pregnancy or have no history of reproductive issues may not benefit from this research.

What this research studies

This research investigates the role of glycogen stored in the uterus and its impact on successful pregnancy. It focuses on how the uterine environment supports embryo development, particularly during critical stages of implantation. By examining glucose secretion and uptake in the uterus, the study aims to uncover mechanisms that could lead to improved fertility outcomes. Patients may benefit from insights that could enhance reproductive health and address infertility issues.

Why it matters

Potential benefit: If successful, this research could lead to new strategies for improving fertility and reducing pregnancy complications.

How similar studies have gone: Other research has shown promising results in understanding the role of uterine conditions in pregnancy, suggesting that this approach could yield valuable insights.

Where this research is happening

  • University of Illinois at Urbana-Champaign
    Champaign, United States
    Active

Researchers

  • Principal investigator: Dean, Matthew J — University of Illinois at Urbana-Champaign
  • Study coordinator: Dean, Matthew J

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.