Understanding how uterine contractions affect the placenta during pregnancy
Characterizing the Relationship between Uterine Activity and Placental Function Across Pregnancy with MRI
['FUNDING_R21'] · BOSTON CHILDREN'S HOSPITAL · NIH-10673962
This study is looking at how practice contractions, called Braxton Hicks, affect the placenta and blood flow to the baby during pregnancy, which could help spot any potential issues early on and improve ways to check on your baby's health.
Quick facts
| Phase | ['FUNDING_R21'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | BOSTON CHILDREN'S HOSPITAL (nih funded) |
| Locations | 1 site (BOSTON, UNITED STATES) |
| Trial ID | NIH-10673962 on ClinicalTrials.gov |
What this research studies
This research investigates the relationship between uterine activity, specifically Braxton Hicks contractions, and placental function throughout pregnancy using advanced MRI techniques. By analyzing how these contractions impact blood flow and oxygen transport to the fetus, the study aims to gather quantitative data that could help identify pregnancies at risk for complications like intrauterine growth restriction (IUGR). The findings may lead to the development of new tests to monitor fetal health and placental function more effectively.
Who could benefit from this research
Good fit: Ideal candidates for this research include pregnant individuals experiencing normal or restricted fetal growth.
Not a fit: Patients who are not pregnant or those with conditions unrelated to placental function or fetal growth may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could improve prenatal monitoring and outcomes for fetuses at risk of growth restrictions due to placental dysfunction.
How similar studies have performed: While the specific approach of using MRI to assess uterine contractions and placental function is novel, related research has shown promise in understanding placental health and fetal outcomes.
Where this research is happening
BOSTON, UNITED STATES
- BOSTON CHILDREN'S HOSPITAL — BOSTON, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: ABACI TURK, ESRA — BOSTON CHILDREN'S HOSPITAL
- Study coordinator: ABACI TURK, ESRA
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.