NIH-funded research R01 grant

Understanding how urban and rural environments affect Alzheimer's-related dementia

Official title: Assessing Urban-Rural Environmental Stress Inequities in ADRD through Ecological Momentary Assessment

Funded at Trustees of Indiana University · NIH-10977884 · Data updated 2026-11-12

This study is looking at how different stressors in city and country living can affect the risk of developing Alzheimer's-related dementia, and it's for people in Indiana who are at higher risk; you'll use a mobile app to share your experiences and wear a smartwatch to track your health over two weeks.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionTrustees of Indiana University
NIH-funded
Lab location1 site (Bloomington, United States)
Project startJuly 10, 2024
Project endJune 30, 2029
Funding year2024
Award (this year)$817,345
NIH project number1R01NS139192-01
Project IDNIH-10977884 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates are individuals aged 65 and older who are at high risk for developing Alzheimer's-related dementia and have mild cognitive impairment.

Less likely to help

Patients who do not have mild cognitive impairment or are younger than 65 years old may not benefit from this research.

What this research studies

This research investigates the impact of environmental stressors on the development of Alzheimer's Disease-Related Dementias (ADRD) in urban and rural populations. It will involve 600 participants from Indiana, half of whom live in urban areas and half in rural settings, all identified as high risk for ADRD. Participants will use a mobile app to report their stressors over two weeks while their physical activity and health data are monitored through a smartwatch. The goal is to analyze how these environmental factors contribute to health inequities in dementia.

Why it matters

Potential benefit: If successful, this research could lead to improved understanding and interventions for reducing the risk of Alzheimer's-related dementia based on environmental factors.

How similar studies have gone: Previous research has shown success in using ecological momentary assessment to understand health behaviors and stressors, suggesting this approach may yield valuable insights.

Where this research is happening

  • Trustees of Indiana University
    Bloomington, United States
    Active

Researchers

  • Principal investigator: Jordan, Evan — Trustees of Indiana University
  • Study coordinator: Jordan, Evan

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.