Understanding how uncertain genomic variants affect cancer treatment decisions
Multilevel investigation of uncertain and reclassified genomic variants in clinical oncology
['FUNDING_OTHER'] · UT SOUTHWESTERN MEDICAL CENTER · NIH-10905019
This study is looking at how confusing genetic test results can affect decisions about cancer care, and it aims to create helpful tools for patients and doctors to better understand these results, especially for people from different racial and ethnic backgrounds.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UT SOUTHWESTERN MEDICAL CENTER (nih funded) |
| Locations | 1 site (DALLAS, UNITED STATES) |
| Trial ID | NIH-10905019 on ClinicalTrials.gov |
What this research studies
This research investigates how uncertain and reclassified genomic variants impact clinical decision-making in oncology. By collecting data from diverse patient populations across multiple healthcare systems, the study aims to design interventions that help patients and providers navigate the complexities of these genetic variants. The research incorporates psychosocial and behavioral concepts to improve communication and decision-making processes regarding cancer prevention and treatment. It also focuses on the unique challenges faced by racial and ethnic minority groups in understanding their genomic information.
Who could benefit from this research
Good fit: Ideal candidates for this research include cancer patients who have received genomic testing and are facing uncertainty regarding their results.
Not a fit: Patients who do not have genomic testing or those with well-defined genetic variants may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved decision-making and treatment options for cancer patients based on their genomic information.
How similar studies have performed: Previous research has shown that addressing the complexities of genomic variants can enhance patient understanding and improve clinical outcomes, indicating a promising approach.
Where this research is happening
DALLAS, UNITED STATES
- UT SOUTHWESTERN MEDICAL CENTER — DALLAS, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: MAKHNOON, SUKH — UT SOUTHWESTERN MEDICAL CENTER
- Study coordinator: MAKHNOON, SUKH
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Cancer Patient, Cancers, Comprehensive Cancer Center