Understanding how Type III collagen affects tendon development and healing in newborns
Official title: Defining the Role of Type III Collagen in Neonatal Tendon Development and Healing
Funded at University of Pennsylvania · NIH-10992656 · Data updated 2026-11-12
This study is looking at how a special type of collagen helps newborns' tendons grow and heal, with the goal of finding better ways to help tendons recover from injuries.
Quick facts
| Grant type | Fellowship grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Pennsylvania NIH-funded |
| Lab location | 1 site (Philadelphia, United States) |
| Project start | December 7, 2022 |
| Project end | December 6, 2025 |
| Funding year | 2025 |
| Award (this year) | $36,736 |
| NIH project number | 5F31AR082282-03 |
| Project ID | NIH-10992656 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are neonates and young individuals with tendon injuries or developmental concerns.
✕Less likely to help
Patients with fully developed tendons or those who are not in the neonatal or young age group may not benefit from this research.
What this research studies
This research investigates the role of Type III collagen in the development and healing of tendons in neonates. It aims to understand how this collagen type contributes to the structural integrity and healing efficiency of tendons, which are crucial for movement and function. By examining the differences between neonatal tendon development and healing in adults, the research seeks to identify ways to enhance tendon repair through tissue engineering. The approach includes modulating collagen properties and studying cellular activities involved in tendon healing.
Why it matters
Potential benefit: If successful, this research could lead to improved treatments for tendon injuries, particularly in newborns and young patients.
How similar studies have gone: While the role of collagen in tendon healing has been studied, this specific focus on Type III collagen in neonatal tendon development is relatively novel.
Where this research is happening
-
University of Pennsylvania
Philadelphia, United States Active
Researchers
- Principal investigator: Tamburro, Margaret Kathryn — University of Pennsylvania
- Study coordinator: Tamburro, Margaret Kathryn
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.