Understanding how Type 1 Diabetes affects young children's thinking and learning

Neurocognitive Effects of Type 1 Diabetes in Young Children: Indiana University Clinical Center

['FUNDING_U01'] · INDIANA UNIVERSITY INDIANAPOLIS · NIH-11168881

This project looks at how Type 1 diabetes might affect the brains and thinking skills of young children, especially those diagnosed early in life.

Quick facts

Phase['FUNDING_U01']
Study typeNih_funding
SexAll
SponsorINDIANA UNIVERSITY INDIANAPOLIS (nih funded)
Locations1 site (INDIANAPOLIS, UNITED STATES)
Trial IDNIH-11168881 on ClinicalTrials.gov

What this research studies

This project aims to understand why some children with Type 1 diabetes experience difficulties with thinking and learning. Researchers will look at how the disease impacts brain development and structure in children diagnosed at a young age. They also want to find out what factors might protect children or put them at higher risk for these changes. Additionally, the project will explore if newer diabetes management technologies play a role in children's brain health and cognitive abilities. This work involves a team of experts to gather information from children with Type 1 diabetes and healthy children.

Who could benefit from this research

Good fit: Ideal candidates are children with Type 1 diabetes, particularly those diagnosed early in life, and healthy children, specifically in the 6 to under 8 years age range.

Not a fit: Patients outside the specified age range or those without Type 1 diabetes (unless serving as healthy controls) may not directly benefit from participation in this specific phase of the research.

Why it matters

Potential benefit: If successful, this work could lead to new ways to protect the brains of young children with Type 1 diabetes and improve their long-term learning and daily functioning.

How similar studies have performed: While the link between early-onset Type 1 diabetes and cognitive issues is known, this project aims to fill gaps in understanding the underlying causes and protective factors, making its specific approach novel in its comprehensive scope.

Where this research is happening

INDIANAPOLIS, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.