Understanding how type 1 diabetes affects heart and blood pressure during exercise
Official title: Mechanisms of Type 1 Diabetes in the Autonomic Control of Circulation During Exercise
Funded at University of Texas at Austin · NIH-11097187 · Data updated 2026-11-12
This study looks at how type 1 diabetes affects your heart rate and blood pressure when you exercise, with the goal of finding ways to keep you safer and healthier during physical activity.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Texas at Austin NIH-funded |
| Lab location | 1 site (Austin, United States) |
| Project start | June 1, 2023 |
| Project end | May 31, 2028 |
| Funding year | 2025 |
| Award (this year) | $717,252 |
| NIH project number | 5R01HL166323-03 |
| Project ID | NIH-11097187 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals diagnosed with type 1 diabetes who engage in physical activity.
✕Less likely to help
Patients without type 1 diabetes or those who do not participate in physical activity may not benefit from this research.
What this research studies
This research investigates how type 1 diabetes (T1D) impacts the body's ability to control heart rate and blood pressure during physical activity. It aims to identify specific mechanisms that lead to dangerous cardiovascular responses, such as heart attacks or strokes, when individuals with T1D exercise. By studying the roles of certain receptors in the body, the research seeks to improve health outcomes and reduce the risk of severe cardiovascular events in patients with T1D. The findings could lead to better management strategies for those affected by this condition.
Why it matters
Potential benefit: If successful, this research could significantly reduce the risk of cardiovascular events in patients with type 1 diabetes during exercise.
How similar studies have gone: Previous research has shown that understanding cardiovascular responses in diabetes can lead to improved treatment strategies, indicating potential success for this approach.
Where this research is happening
-
University of Texas at Austin
Austin, United States Active
Researchers
- Principal investigator: Stone, Audrey J — University of Texas at Austin
- Study coordinator: Stone, Audrey J
Related research
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-
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Treating impaired hypoglycemia awareness in type 1 diabetes with targeted education and technology
This study tests two treatment approaches to help adults with type 1 diabetes who often don’t realize their blood sugar is getting too low, using a mix of technology and education in two large groups.
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A UK study tests two different approaches to help adults with type 1 diabetes recognize and respond to low blood sugar by comparing a high-tech insulin system with targeted education.
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How the pancreas environment affects insulin-producing cells in type 1 diabetes
Researchers are studying how the surrounding tissue of the pancreas and its proteins influence insulin-producing cells in people with type 1 diabetes.
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Understanding how hypoglycemia awareness changes in adults with type 1 diabetes and how automated insulin delivery and exercise might help restore it
This study will look at adults with type 1 diabetes to see how their awareness of low blood sugar evolves over time and whether automated insulin delivery and high-intensity exercise can help restore that awareness.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.