Understanding how type 1 diabetes affects brain function in young children
Official title: Determinants of Neurocognitive Complications in T1D
Funded at University of Colorado Denver · NIH-10974115 · Data updated 2026-11-12
This study is looking at how type 1 diabetes affects kids' thinking and brain health over three years, especially how things like low or high blood sugar can impact their everyday lives and development.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Colorado Denver NIH-funded |
| Lab location | 1 site (Aurora, UNITED STATES) |
| Project start | August 15, 2024 |
| Project end | June 30, 2029 |
| Funding year | 2024 |
| Award (this year) | $271,385 |
| NIH project number | 1U01DK140735-01 |
| Project ID | NIH-10974115 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are children aged 0-11 years who have recently been diagnosed with type 1 diabetes.
✕Less likely to help
Patients who are older than 11 years or do not have a diagnosis of type 1 diabetes may not benefit from this research.
What this research studies
This research investigates the cognitive impairments and brain changes that occur in children with type 1 diabetes (T1D). It aims to understand how factors like episodes of low blood sugar, high blood sugar, and diabetic ketoacidosis impact brain function and overall quality of life. By enrolling children diagnosed with T1D, the study will follow them over three years to collect data on their cognitive and psychosocial development. The goal is to identify the long-term effects of these diabetes-related factors on children's brain health.
Why it matters
Potential benefit: If successful, this research could lead to improved management strategies for children with type 1 diabetes, enhancing their cognitive health and quality of life.
How similar studies have gone: Previous research has indicated that cognitive impairments in children with diabetes are a significant concern, suggesting that this study's approach is both relevant and necessary.
Where this research is happening
-
University of Colorado Denver
Aurora, United States Active
Researchers
- Principal investigator: Rewers, Marian J — University of Colorado Denver
- Study coordinator: Rewers, Marian J
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.