Understanding how type 1 diabetes affects brain function in young children

Determinants of Neurocognitive Complications in T1D

['FUNDING_U01'] · UNIVERSITY OF COLORADO DENVER · NIH-10974115

This study is looking at how type 1 diabetes affects kids' thinking and brain health over three years, especially how things like low or high blood sugar can impact their everyday lives and development.

Quick facts

Phase['FUNDING_U01']
Study typeNih_funding
SexAll
SponsorUNIVERSITY OF COLORADO DENVER (nih funded)
Locations1 site (Aurora, UNITED STATES)
Trial IDNIH-10974115 on ClinicalTrials.gov

What this research studies

This research investigates the cognitive impairments and brain changes that occur in children with type 1 diabetes (T1D). It aims to understand how factors like episodes of low blood sugar, high blood sugar, and diabetic ketoacidosis impact brain function and overall quality of life. By enrolling children diagnosed with T1D, the study will follow them over three years to collect data on their cognitive and psychosocial development. The goal is to identify the long-term effects of these diabetes-related factors on children's brain health.

Who could benefit from this research

Good fit: Ideal candidates for this research are children aged 0-11 years who have recently been diagnosed with type 1 diabetes.

Not a fit: Patients who are older than 11 years or do not have a diagnosis of type 1 diabetes may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved management strategies for children with type 1 diabetes, enhancing their cognitive health and quality of life.

How similar studies have performed: Previous research has indicated that cognitive impairments in children with diabetes are a significant concern, suggesting that this study's approach is both relevant and necessary.

Where this research is happening

Aurora, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Conditions: Brittle Diabetes Mellitus, Childhood diabetes

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.