Understanding how Type 1 diabetes affects brain development in young children
Official title: Neurocognitive Effects of Type 1 Diabetes in Young Children: Indiana University Clinical Center
Funded at Indiana University Indianapolis · NIH-10975193 · Data updated 2026-11-12
This study is looking at how Type 1 diabetes affects the thinking skills of children diagnosed before age 6, and it aims to understand how diabetes management tools can help improve their brain health compared to kids without diabetes.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Indiana University Indianapolis NIH-funded |
| Lab location | 1 site (Indianapolis, United States) |
| Project start | August 15, 2024 |
| Project end | June 30, 2029 |
| Funding year | 2024 |
| Award (this year) | $270,932 |
| NIH project number | 1U01DK140782-01 |
| Project ID | NIH-10975193 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are children aged 6 years and younger who have been diagnosed with Type 1 diabetes.
✕Less likely to help
Patients who are older than 21 years or do not have Type 1 diabetes may not benefit from this research.
What this research studies
This research investigates the cognitive impairments associated with Type 1 diabetes (T1D) in children, particularly those diagnosed before the age of 6. It aims to explore how T1D impacts brain structure and function, and to identify risk and protective factors that influence cognitive outcomes. The study will involve collaboration among pediatric endocrinologists, psychologists, and radiologists to assess the relationship between diabetes management technologies and cognitive performance in young patients. By comparing children with T1D to healthy controls, the research seeks to fill knowledge gaps regarding neurocognitive changes in this population.
Why it matters
Potential benefit: If successful, this research could lead to improved strategies for managing cognitive health in children with Type 1 diabetes.
How similar studies have gone: Previous research has indicated cognitive impairments in children with Type 1 diabetes, suggesting that this study builds on established findings rather than exploring a completely novel area.
Where this research is happening
-
Indiana University Indianapolis
Indianapolis, United States Active
Researchers
- Principal investigator: Dimeglio, Linda a — Indiana University Indianapolis
- Study coordinator: Dimeglio, Linda a
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.