Understanding how Type 1 diabetes affects brain development in young children

Neurocognitive Effects of Type 1 Diabetes in Young Children: Indiana University Clinical Center

['FUNDING_U01'] · INDIANA UNIVERSITY INDIANAPOLIS · NIH-10975193

This study is looking at how Type 1 diabetes affects the thinking skills of children diagnosed before age 6, and it aims to understand how diabetes management tools can help improve their brain health compared to kids without diabetes.

Quick facts

Phase['FUNDING_U01']
Study typeNih_funding
SexAll
SponsorINDIANA UNIVERSITY INDIANAPOLIS (nih funded)
Locations1 site (INDIANAPOLIS, UNITED STATES)
Trial IDNIH-10975193 on ClinicalTrials.gov

What this research studies

This research investigates the cognitive impairments associated with Type 1 diabetes (T1D) in children, particularly those diagnosed before the age of 6. It aims to explore how T1D impacts brain structure and function, and to identify risk and protective factors that influence cognitive outcomes. The study will involve collaboration among pediatric endocrinologists, psychologists, and radiologists to assess the relationship between diabetes management technologies and cognitive performance in young patients. By comparing children with T1D to healthy controls, the research seeks to fill knowledge gaps regarding neurocognitive changes in this population.

Who could benefit from this research

Good fit: Ideal candidates for this research are children aged 6 years and younger who have been diagnosed with Type 1 diabetes.

Not a fit: Patients who are older than 21 years or do not have Type 1 diabetes may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved strategies for managing cognitive health in children with Type 1 diabetes.

How similar studies have performed: Previous research has indicated cognitive impairments in children with Type 1 diabetes, suggesting that this study builds on established findings rather than exploring a completely novel area.

Where this research is happening

INDIANAPOLIS, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.