Understanding how type 1 diabetes affects bone health in young people
Determinants of bone microarchitectural compromise in youth with type 1 diabetes
This study is looking at how type 1 diabetes affects bone health in kids and young adults aged 6 to 20, comparing them to their friends without diabetes to find out why they might be more likely to break bones, with the goal of helping improve bone health for those with diabetes.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Massachusetts General Hospital NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project ID | NIH-10693855 on NIH RePORTER |
What this research studies
This research investigates how type 1 diabetes (T1D) impacts bone development in children and young adults aged 6 to 20 years. By comparing the bone health of those with T1D to their non-diabetic peers, the study aims to identify specific factors that contribute to increased fracture risk. The approach involves a prospective observational study that collects data over two years to better understand the mechanisms behind skeletal fragility in this population. The findings could lead to improved strategies for monitoring and enhancing bone health in youth with diabetes.
Who could benefit from this research
Good fit: Ideal candidates for this research are children and young adults aged 6 to 20 years who have been diagnosed with type 1 diabetes.
Not a fit: Patients who do not have type 1 diabetes or are outside the age range of 6 to 20 years may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better prevention and treatment strategies for bone fractures in young individuals with type 1 diabetes.
How similar studies have performed: Previous research has indicated that understanding the relationship between diabetes and bone health is crucial, but this specific approach to studying youth with T1D is relatively novel.
Where this research is happening
Boston, United States
- Massachusetts General Hospital — Boston, United States (Active)
Researchers
- Principal investigator: Mitchell, Deborah Michelle — Massachusetts General Hospital
- Study coordinator: Mitchell, Deborah Michelle
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.