Understanding how tumors interact with the immune system
Official title: Project 2: Deciphering the Dynamic Evolution of the Tumor-Immune Interface
Funded at Massachusetts Institute of Technology · NIH-10930073 · Data updated 2026-11-12
This study is looking at how tumors and the immune system work together over time, with the goal of finding new ways to help patients fight cancer by improving their immune response.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Massachusetts Institute of Technology NIH-funded |
| Lab location | 1 site (Cambridge, United States) |
| Project start | September 15, 2023 |
| Project end | August 31, 2028 |
| Funding year | 2024 |
| Award (this year) | $422,043 |
| NIH project number | 5U54CA283114-02 |
| Project ID | NIH-10930073 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include patients with glioblastoma or other cancers that exhibit immunosuppressive characteristics.
✕Less likely to help
Patients with non-cancerous conditions or those whose tumors do not interact significantly with the immune system may not benefit from this research.
What this research studies
This research investigates the complex interactions between tumors and the immune system, focusing on how these interactions evolve over time. By using advanced techniques to analyze molecular and cellular changes, the project aims to identify key pathways that contribute to tumor growth and resistance to therapies. Patients may benefit from insights gained through this research, which could lead to the development of new treatment strategies that enhance immune responses against tumors. The research employs both laboratory models and animal studies to validate findings and improve understanding of tumor-immune dynamics.
Why it matters
Potential benefit: If successful, this research could lead to new therapeutic strategies that improve patient outcomes in cancer treatment.
How similar studies have gone: Previous research has shown promise in understanding tumor-immune interactions, suggesting that this approach could yield valuable insights.
Where this research is happening
-
Massachusetts Institute of Technology
Cambridge, United States Active
Researchers
- Principal investigator: White, Forest M — Massachusetts Institute of Technology
- Study coordinator: White, Forest M
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.