Understanding how tumors develop in U.S. Veterans
Mutational processes underlying tumor development in United States Veterans
['FUNDING_OTHER'] · PHILADELPHIA VA MEDICAL CENTER · NIH-10975944
This study is looking at how certain changes in genes cause cancer in U.S. Veterans, with the hope of finding new ways to improve cancer treatments that work better for patients.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | PHILADELPHIA VA MEDICAL CENTER (nih funded) |
| Locations | 1 site (PHILADELPHIA, UNITED STATES) |
| Trial ID | NIH-10975944 on ClinicalTrials.gov |
What this research studies
This research investigates the mutational processes that lead to tumor development specifically in U.S. Veterans. By utilizing whole genome sequencing, the study aims to identify unique mutational signatures that contribute to cancer, which may not be captured by current clinical tests focusing on single genomic alterations. The goal is to develop new tumor biomarkers that can enhance precision oncology, ultimately leading to more effective treatment options for patients. This approach addresses the limitations of existing therapies that often fail to benefit a significant number of cancer patients.
Who could benefit from this research
Good fit: Ideal candidates for this research are U.S. Veterans diagnosed with cancer who may benefit from advanced genomic analysis.
Not a fit: Patients who do not have a cancer diagnosis or are not U.S. Veterans may not receive any benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved cancer treatments tailored specifically for Veterans, enhancing their chances of successful outcomes.
How similar studies have performed: Previous research has shown promise in identifying mutational signatures in cancer, suggesting that this approach could yield valuable insights, although it may also be considered a novel exploration in the context of Veteran populations.
Where this research is happening
PHILADELPHIA, UNITED STATES
- PHILADELPHIA VA MEDICAL CENTER — PHILADELPHIA, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: MAXWELL, KARA N — PHILADELPHIA VA MEDICAL CENTER
- Study coordinator: MAXWELL, KARA N
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Cancer Patient, Cancers