Understanding how tubular lysosomes function in health and disease
Tubular lysosomes in health and disease
['FUNDING_OTHER'] · LOUISIANA STATE UNIV A&M COL BATON ROUGE · NIH-10891630
This study is looking at how tiny structures in our cells called lysosomes might change as we age and how that could lead to diseases like Alzheimer's and ALS, with the hope of finding new ways to help keep these structures working well and improve health for people facing these conditions.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | LOUISIANA STATE UNIV A&M COL BATON ROUGE (nih funded) |
| Locations | 1 site (BATON ROUGE, UNITED STATES) |
| Trial ID | NIH-10891630 on ClinicalTrials.gov |
What this research studies
This research investigates the role of tubular lysosomes in age-related degenerative diseases like Alzheimer's and ALS. It aims to uncover the molecular mechanisms behind lysosome function and how their impairment contributes to disease progression. By studying these organelles in various biological contexts, the research seeks to identify potential therapeutic strategies to enhance lysosome function and combat degenerative diseases. The approach includes using model organisms such as flies and worms to explore the genetic factors involved in lysosome maintenance.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with age-related degenerative diseases, particularly those with Alzheimer's or ALS.
Not a fit: Patients with non-degenerative conditions or those not affected by age-related diseases may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatments that improve lysosome function and potentially slow down or reverse the progression of degenerative diseases.
How similar studies have performed: Previous research has shown promising results in understanding lysosome function and its implications in degenerative diseases, suggesting that this approach could yield significant insights.
Where this research is happening
BATON ROUGE, UNITED STATES
- LOUISIANA STATE UNIV A&M COL BATON ROUGE — BATON ROUGE, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: JOHNSON, ALYSSA — LOUISIANA STATE UNIV A&M COL BATON ROUGE
- Study coordinator: JOHNSON, ALYSSA
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Alzheimer disease dementia, Alzheimer syndrome, Alzheimer's Disease