Understanding how tuberculosis affects blood sugar and metabolism
Official title: Multiomics Characterization of Micobiome and Immunometabolic REmodeling in Tuberculosis Stress Hyperglycemia
Funded at Emory University · NIH-11064045 · Data updated 2026-11-12
This study is looking at how having tuberculosis might affect your blood sugar and increase the risk of diabetes over time, and it's for people who have had tuberculosis and want to understand how it could impact their health after treatment.
Quick facts
| Grant type | R21 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Emory University NIH-funded |
| Lab location | 1 site (Atlanta, United States) |
| Project start | April 1, 2024 |
| Project end | February 28, 2026 |
| Funding year | 2025 |
| Award (this year) | $227,708 |
| NIH project number | 5R21AI178324-02 |
| Project ID | NIH-11064045 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals who have been diagnosed with tuberculosis and are experiencing or at risk for stress hyperglycemia.
✕Less likely to help
Patients who do not have a history of tuberculosis or related metabolic issues may not benefit from this research.
What this research studies
This research investigates the long-term effects of tuberculosis on metabolic health, particularly focusing on how it can lead to stress hyperglycemia and increase the risk of diabetes. By studying a unique group of patients from Georgia, the research aims to track changes in blood sugar levels and metabolic health over 18 months during and after tuberculosis treatment. The goal is to uncover the mechanisms behind these changes to develop new therapies that can improve health outcomes for individuals affected by tuberculosis.
Why it matters
Potential benefit: If successful, this research could lead to new treatments that improve metabolic health and reduce mortality in patients recovering from tuberculosis.
How similar studies have gone: Previous research has shown promising results in understanding the relationship between tuberculosis and metabolic health, indicating that this approach has potential for significant insights.
Where this research is happening
-
Emory University
Atlanta, United States Active
Researchers
- Principal investigator: Collins, Jeffrey M — Emory University
- Study coordinator: Collins, Jeffrey M
Related research
Other NIH-funded projects on the same topics.
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How stress-related high blood sugar affects tuberculosis treatment and diabetes risk
This study is looking at how stress-related high blood sugar affects the treatment of tuberculosis (TB) and whether it increases the chances of developing diabetes afterward, specifically for patients in places like Georgia where both conditions are common.
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.